HiClamp

Please note: Currently, our publications library includes articles up to 2021 only. Contact us for publications from 2022 – present. Contact Us

Alijevic O, McHugh D, Rufener L, Mazurov A, Hoeng J, Peitsch M (2020) An electrophysiological characterization of naturally occurring tobacco alkaloids and their action on human alpha4beta2 and alpha7 nicotinic acetylcholine receptors. Phytochemistry 170:112187.

Brams M, Govaerts C, Kambara K, Price KL, Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SCR, Hibbs RE, Steyaert J, Ulens C (2020) Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site. Elife 9:e51511.

Zeng SL, Sudlow LC, Berezin MY (2020) Using Xenopus oocytes in neurological disease drug discovery. Expert Opin Drug Discov 15:39-52.

Brams M, Govaerts C, Kambara K, Price KL, Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SCR, Hibbs RE, Steyaert J, Ulens C (2019) A Functionally Conserved Mechanism of Modulation via a Vestibule Site in Pentameric Ligand-Gated Ion Channels. bioRxiv:770719.

Brissonnet Y, Araoz R, Sousa R, Percevault L, Brument S, Deniaud D, Servent D, Le Questel JY, Lebreton J, Gouin SG (2019) Di- and heptavalent nicotinic analogues to interfere with alpha7 nicotinic acetylcholine receptors. Bioorg Med Chem 27:700-707.

Gonzalez-Gutierrez JP, Hodar M, Viscarra F, Paillali P, Guerra-Diaz N, Pessoa-Mahana H, Hernandez-Morantes JJ, Perez-Sanchez H, Bermudez I, Reyes-Parada M, Iturriaga-Vasquez P (2019) Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues. Molecules 24.

Moraga-Nicolás F, Iturriaga-Vásquez P, Mutis A, Hormazábal E, Bermúdez-Díaz I (2019) Galanthamine and other Amaryllidaceae related alkaloids are inhibitors of α7, α4β2 and α3β4 nicotinic acetylcholine receptors. Revista Brasileira de Farmacognosia.

Nielsen BE, Bermudez I, Bouzat C (2019) Flavonoids as positive allosteric modulators of alpha7 nicotinic receptors. Neuropharmacology:107794.

van Goethem NP, Paes D, Puzzo D, Fedele E, Rebosio C, Gulisano W, Palmeri A, Wennogle LP, Peng Y, Bertrand D, Prickaerts J (2019) Antagonizing alpha7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition. Cell Signal 62:109338.

Danthi SJ, Liang B, Smicker O, Coupland B, Gregory J, Gefteas E, Tietz D, Klodnitsky H, Randall K, Belanger A, Kuntzweiler TA (2018) Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays. SLAS Discov:2472555218794627.

Knoflach F, Hernandez M, Bertrand D (2018) Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. JoVE:e57842.

Oliveira B (2018) Genetic and autoimmune modulators of brain function in neuropsychiatric illness and health Division of Mathematics and Natural Sciences

Bretin S, Louis C, Seguin L, Wagner S, Thomas JY, Challal S, Rogez N, Albinet K, Iop F, Villain N, Bertrand S, Krazem A, Berachochea D, Billiald S, Tordjman C, Cordi A, Bertrand D, Lestage P, Danober L (2017) Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors. PLoS ONE 12:e0184429.

Callahan PM, Bertrand D, Bertrand S, Plagenhoef MR, Terry AV (2017) Tropisetron sensitizes α7 containing nicotinic receptors to low levels of acetylcholine in vitro and improves memory-related task performance in young and aged animals. Neuropharmacology 117:422-433.

Giralt A, Gomez-Climent MA, Alcala R, Bretin S, Bertrand D, Maria Delgado-Garcia J, Perez-Navarro E, Alberch J, Gruart A (2017) The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice. Neuropharmacology 123:395-409.

Principalli MA, Lemel L, Rongier A, Godet AC, Langer K, Revilloud J, Darre L, Domene C, Vivaudou M, Moreau CJ (2017) Functional mapping of the N-terminal arginine cluster and C-terminal acidic residues of Kir6.2 channel fused to a G protein-coupled receptor. Biochim Biophys Acta 1859:2144-2153.

Rufener L, Danelli V, Bertrand D, Sager H (2017) The novel isoxazoline ectoparasiticide lotilaner (Credelio): a non-competitive antagonist specific to invertebrates gamma-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors 10:530.

Vivaudou M, Todorov Z, Reyes-Mejia GC, Moreau C (2017) Ion Channels as Reporters of Membrane Receptor Function: Automated Analysis in Xenopus Oocytes. In: Membrane Protein Structure and Function Characterization: Methods and Protocols (Lacapere J-J, ed): Springer.

Bürgi JJ, Bertrand S, Marger F, Bertrand D, Reymond J-L (2016) Fluorescent Agonists of the α7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine. Helvetica Chimica Acta 99:790-804.

Reyes-Mejia GC (2016) Molecular studies of ATP-sensitive potassium channels: Gating, pathology, and optogenetics

Wijckmans E, Nys M, Debaveye S, Brams M, Pardon E, Willegems K, Bertrand D, Steyaert J, Efremov R, Ulens C (2016) Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues. PLoS ONE 11:e0151183.

Eggert M, Winterer G, Wanischeck M, Hoda JC, Bertrand D, Steinlein O (2015) The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype. BMC Genet 16:46.

Moreau CJ, Niescierowicz K, Caro LN, Revilloud J, Vivaudou M (2015) Ion channel reporter for monitoring the activity of engineered GPCRs. Methods Enzymol 556:425-454.

Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, Graff A, Stahlberg H, Tomizaki T, Desmyter A, Moreau C, Li XD, Poitevin F, Vogel H, Nury H (2014) X-ray structure of the mouse serotonin 5-HT3 receptor. Nature 512:276-281.

Juneja P, Horlacher R, Bertrand D, Krause R, Marger F, Welte W (2014) An Internally Modulated, Thermostable, pH-sensitive Cys Loop Receptor from the Hydrothermal Vent Worm Alvinella pompejana. Journal of Biological Chemistry 289:15130-15140.

Niescierowicz K, Caro L, Cherezov V, Vivaudou M, Moreau CJ (2014) Functional assay for T4 lysozyme-engineered G protein-coupled receptors with an ion channel reporter. Structure 22:149-155.

Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price KL, Weston DA, Strelkov SV, Tytgat J, Bertrand S, Bertrand D, Lummis SC, Ulens C (2013) Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). J Biol Chem 288:8355-8364.

Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK (2013) Assembly of a pi-pi stack of ligands in the binding site of an acetylcholine-binding protein. Nat Commun 4:1875.

Favreau P, Benoit E, Hocking HG, Carlier L, D' hoedt D, Leipold E, Markgraf R, Schlumberger S, Cordova MA, Gaertner H, Paolini-Bertrand M, Hartley O, Tytgat J, Heinemann SH, Bertrand D, Boelens R, Stocklin R, Molgo J (2012) A novel micro-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors. Br J Pharmacol 166:1654-1668.

Murray TA, Bertrand D, Papke RL, George AA, Pantoja R, Srinivasan R, Liu Q, Wu J, Whiteaker P, Lester HA, Lukas RJ (2012) alpha7beta2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their alpha7-alpha7 interfaces. Mol Pharmacol 81:175-188.

Prickaerts J, van Goethem NP, Chesworth R, Shapiro G, Boess FG, Methfessel C, Reneerkens OA, Flood DG, Hilt D, Gawryl M, Bertrand S, Bertrand D, Konig G (2012) EVP-6124, a novel and selective alpha7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha7 nicotinic acetylcholine receptors. Neuropharmacology 62:1099-1110.

Utkin YN, Weise C, Kasheverov IE, Andreeva TV, Kryukova EV, Zhmak MN, Starkov VG, Hoang NA, Bertrand D, Ramerstorfer J, Sieghart W, Thompson AJ, Lummis SC, Tsetlin VI (2012) Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem 287:27079-27086.