Multi Channel Experimenter

Software Version:

V 2.20.15

Release Date:

2024-04-16

Software Download:

Tool for data acquisition and online analysis. Compatible with all MEA2100-Systems, (USB-)ME16/32/64/128/256-Systems, and Wireless-/W2100-Systems. Part of the Multi Channel Suite.

Compatible with Windows^® 7 /8.x / 10 (64 Bit).

Note: To use the latest features in combination with a W2100-System please use the latest W2100-Config software to update the firmware of the system and headstages.

Product Category:

Products

Software

In vitro / in vivo Systems

Multi Channel Suite

References

Release Notes

Version 2.20.15

Bug fix in Burst Analyzer if inconsistent interval parameters are set
Increased a data buffer size to improve performance

Version 2.20.14

Much better error handling when an USB error occurs. Should greatly reduce crashes of the Experimenter without an error message
Reduced occurrences of "ring queue overflow"
SCU devices: fix crash when activating an instance when more than one instance is running
Fix for multi well layout which is enabled after a change of the selected array while data acquisition is running
Fix for a crash which can occur if a channel is focused in a well and the well is switched to a well which does not contain that channel

Version 2.20.9

Added 0.05 Hz to the allowed high-pass filter frequencies.
Support for Fresco Logic USB extension card
Many bug fixes

Version 2.20.7

Important bugfix for the MEA2100-256 device: In version 2.20.5 of the software the channels are shifted by 2. This version should therefore no longer be used for the device. Earlier versions of the software are not affected by the problem.
Bugfixes for the 'Start on Data Acquisition' option of the digital out stimulator and the electrical stimulator for different devices.
List mode worked properly only for the first stimulator channel.
Now larger values are possible for the pre trigger and the post trigger of the PSTH instrument.

Version 2.20.5

added 0.05 Hz to the allowed high-pass filter frequencies.
removed broken Display Layout. Use custom MEA layouts instead.
fix event related export if an event occurs before the first raw data.

Version 2.20.4

W2100: Fix crash when data source does not have a headstage
Fixes for deleting/changing connections, mainly concerning an X-Channel instrument

Version 2.20.2

fix MEA2100-Mini power save

Version 2.20.1

compatibility update

Version 2.20.0

LFP detection for W2100 realtime feedback
Custom Layouts can be loaded in Experimenter

Version 2.19.0

Several bug fixes

Version 2.18.0

New: Averages: Calculation and display in Sweeps instrument- Improved: Handling of MEA2100-256 unknown headstage type
Improved: Validation of W2100 stimulator input values, also after loading pattern from file. This is important when headstages with different maximum current values are used
Allow feedback as start mode for MEA2100-Mini stimulator
Improved: Sweeps trace colors in Red Light mode
Overlay display of sweeps
W2100: fix wrong sample rate if channels are selected and the max. sample rate is reduced
Set IFB I/O voltage default to 3 .3 V (instead of 5 V)

Firmware updates

W2100: Improved stability for sending commands to headstages
Fix for devices connected to Port B (caused various error messages in Experimenter)

Notable bug fixes

USB-ME devices: Fix for missing audio channels after loading from Experiment Setup
fix crash when using MEA2100 6-well MEA
fix for sometimes missing STG LEDs in status bar
description in Recorder now saved, so that it is exported to HDF5 file with DataManager
Sweeps Explorer: improved navigation through sweeps

Version 2.17.8

Fix: W2100 electrical stimulator amplitude validation

Version 2.17.7

Fix: MEA2100-Mini, ME2100 stimulator events

Version 2.17.6

Fix: W2100 stimulator IO curve current range

Version 2.17.5

New feature: MEA2100-Mini: Start stimulator on feedback

Version 2.17.4

W2100-256: Fix crash when trying to record data when Experiment Setup is loaded
Wrong colors in Filter zoom display in Dark Mode

Version 2.17.3

fix for not writing unit string (problems when exporting data)
fix for certain file names causing recording settings files (msrs) to be mistakenly deleted
MEA2100-256: Do not crash when opening GUI after loading Experiment Setup with no hardware connected

Version 2.17.2

MEA2100-Mini: Power Save feature
Show IFB IO voltage if applicable
Bugfix:
- MEA2100-256: Filter display does not show data and Recorder problems if loaded from Experiment Setup

Version 2.16.0

Display of stimulator events in Data Acquisition Raw Data Display (MEA2100, MEA2100-256 and SCU Devices)
Calculation of absolute area in Sweep Analyzer
Usability improvements for more instrument display windows
W2100 layout "NeuroNexus 4x4 Double" added
Support for IFB 2
Bugfix:
- fix for missing DLL in Setup
- performance improvement when opening an instrument window (regression in the previous version)
W2100 USB 2.0 IFB requires firmware update

Version 2.15.0

support for MEA2100-Mini 120
support for ME2100 32 Headstage (mixed with old HS only possible in multi instance mode)
3D MEA layouts added
improved usability of some displays
better handling of network connection loss in VideoSync
Firmware: New versions with support for new hardware but no new features
Bugfix:
- fix for selecting W2100 layouts
- yet another fix for realtime feedback firmware upload
- pre trigger in Sweep Analyzer Display
- fixed some bugs for loading an Experiment Setup with Stimulator

Version 2.14.0

MEA2100 and MEA2100-256: Stimulator List Mode
W2100: Selection of available electrode layouts
Show "Update All" button in firmware update dialog
Firmware: updated MEA2100-256 firmware with stimulator List Mode
Bugfix: realtime feedback firmware upload failed

Version 2.13.5

New firmware for MEA2100-256

Version 2.13.4

New instruments Spike and Burst Analyzer
Support for new MCS-SCU-in-vitro and MEA2100-mini headstage types

Version 2.12.4

MEA2100: Fixed start of stimulator with Digital Input 0

Version 2.12.3

All devices with internal stimulator except W2100: Infinite repeat of pulses did not work
ME2100 / MEA2100-Mini: Fixed crash in stimulator when switching between voltage and current mode
W2100: Fixed a possible crash when switching headstages

Version 2.12.1

Recorder: Option to append number to filename already for first created file
Analog Data Offset Correction
New firmware for W2100 devices, please update with W2100-System Config (V 1.3.16)
Better visibility of selected channel in some displays
W2100: Corrected the sample rate for W4 opto stimulation headstages

Version 2.11.6

Fix for SCU stimulator offset

Version 2.11.4

Bugfix: Fixed error loading the Burst Analyzer
Updated MEA layouts

Version 2.11.3

Analog Data with y axis and possibility to change size of window
Show hardware/firmware filter info for some devices
MEA2100-256: 6-well and 9-well MEA layouts added
Bugfix: Experimenter was unable to record events
Bugfix: Recorder sometimes triggered on wrong event stream

Version 2.10.1

W2100 Optical Stimulation: Fix crash in the stimulator if "Pause Duration" is set to 0 and Repeat > 1
W2100 W4 headstage: Fix crash of headstage if sample rate is 10kHz --> do not allow 10kHz if all 4 channels are selected

Version 2.10.0

Support for MEA2100-256 ADPT B
Support for Smart-Ephys wireless system
Show serial number and adapter type in instrument palette item for certain data acquisition hardware
Audio output enabled for MEA2100-256 and devices with SCU

Version 2.9.3

Failure of download of W2100 stimulus pattern is sometimes not reported
ME2100, MEA2100-Mini, ME2100-µPA: Device is visible again in the instrument palette even if old firmware is installed. A firmware update dialog is displayed when the
Data Acquisition instrument is dragged into the palette. The update should be performed, otherwise some functions of the software won't work as expected.

Version 2.9.2

Fixed bug in ME2100/MEA2100 firmware for 50kHz sampling rate

Version 2.9.1

added layout for EcoFlexMEA36 and MEA2100/MEA2100-Mini 6-well as single layout
added rotated ME2100 Linear16 and Linear32 McsLayouts
ME2100 Support for µPA
support for SCU analog and audio out (requires firmware update)
new: PSTH display instrument
RedLight GUI mode, can be enabled in Settings dialog
real time feedback for W2100 (requires firmware update)
new: directory to save stimulation patterns can be set in Options dialog
MEA2100-256 stimulator is disabled for 6 and 9 well layouts, new adapters needed

Bug fixes:

fix for ME2100 external reference electrode (requires firmware update)
fixed many problems with Cross Channel Tool, especially for ME2100 and W2100
lots of bug fixes concerning the instrument settings when loading an experiment setup
fix for setting W2100 to suspended

Version 2.8.2

Added missing ME2100 / MEA2100-Mini firmware files

Important: Before doing a firmware update please switch to "Single Instance Mode"!

Version 2.8.1

ME2100/MEA2100-Mini Multi Instance Mode
Long Term Display
FlexMEA36 layouts added to ME2100
Show ME2100/MEA2100-Mini headstage serial number in instrument palette
MEA2100-256 realtime feedback
"All in one file" for devices with multiple headstages (and not in Multi Instance Mode)
New firmware for MEA2100-256, ME2100, and MEA2100-Mini

Notable bug fixes

Recorder: Trigger configuration was not working properly in many cases, especially after loading an Experiment Setup file
Stimulator: fix for loading stimulus files which contain a loop construct
Fixed some crashes with the Sweeps instrument

Known Bugs

Several problems loading an Experiment Setup, especially for ME2100 / MEA2100-Mini, when
1. the device has different headstages than in the saved files
2. ME2100 / MEA2100-Mini if device was not connected when the file was loaded
3. file is loaded into a different instance of the software
4. A stimulator / SCU stimulator is used
Data Acquisition device or stimulator might occur twice in the instrument palette after the device is turned off and on again

Version 2.7.3

ME2100 External Reference
Support for MEA2100-Mini
ME2100/MEA2100-Mini: Layout per headstage
Sweep Instrument: Independent Triggers for each headstage
Support for ME2100/MEA2100-Mini SCU stimulator and (Digital Out)
Support for MEA2100-256 6-well and 9-well layouts (including Stimulator and Digital Out)

Version 2.6.0

W2100: Data Acquisition: Overview Display for multiple headstages
Trigger Generator: Manual Events
W2100, MEA2100: STG Sidebands
ME2100: STG Sidebands and Digital Out
ME2100: Selection of external stimulation electrodes
MEA2100-256: Digital Out, STG Sidebands
Bugfix: Recorder: File name generation if a "." is used in the base file name

Version 2.5.3

Preliminary support for MEA2100-256
Digital Output: bit selection and output pattern generation in Data Acquisition instrument
W2100: support for headstages with gyro sensor
W2100: LED stimulation current measurement: warning if setpoint current is not reached
W2100: Video sync requires new version of Multi Channel VideoControl
Bug fixes
- W2100: STG event stream entities were missing in recorded file, only events of first HS were recorded
- W2100: Quality data are now only saved in file for channels corresponding to the headstage
- W2100: Fixes for headstages in Suspend Mode

Version 2.4.4

Channel selection in MEA layout button panel: Select/deselect rows/columns with Shift/Control key pressed when clicking with mouse
Webupdate: Menu on upper right side contains check for software update
Spike Analyzer: Improved visibility of data markers
Sweeps instrument: Pre trigger times of 1, 2, and seconds added
Sweep Analyzer: Export of selectable parameters for selected channel
Recorder: Auto file name generation starts at largest number if files with the given name exist
Recorder: Better error handling when user has no write permissions on data directory
Filter instrument: Added some cutoff frequencies for high pass and low pass filters
Layouts: Hardware ID is displayed as a tooltip on the layout panel buttons
Layouts: Toggle selection of complete row/column with Ctrl/Shift mouse click
W2100 stimulator: Fix loading old stimulus files
Start and Recording buttons are now in a dockable window, also button to start/stop all stimulators
Data Acquisition Zoom Display: Reset zoom button added
Digital Event Detector: Display of all 16 bits
Digital Event Detector: Dead time
Data Acquisition: Lowest x axis interval is 0.5s
W2100: Support for W16 headstage with separate stimulator electrodes
bug fixes

Version 2.3.3.16336

Window docking fixes:
- Fix crash when making window floating by double click on tab
- Window does not open again after it was closed once
W2100 Multi Headstage Mode: Displays show channels for each headstage, they are switched in the Data Acquisition window
USB port warning when a USB3 IFB is connected to a non Intel USB3 port
W2100 firmware update check
W2100 Stimulator
- start/stop on Digital Input
- start delay for each channel
- pulses alternating between both channels (use start delay)
- invert pulse amplitudes (Neuro Stimulator)
- Stimulator status LEDs in W2100 STG GUI and main window status bar

Version 2.2.1.16294

Documentation (Menu 'Help')
Performance improvements for Spike and Burst Analyzer
Show number of USB packet losses (this number should not change during recording)
New MEA2100 firmware (minor improvements and preparation for future features)
Cutouts in Sweep instrument up to 1000 ms

Bugfixes

MEA2100: no stimulator possible for instances 3 and 4
Some controls were not visible on narrow notebook screens → scrollbar added
Fix wrong behavior depending on the order of the connections made in the Experiment Diagram

Please note: Works only with 64 bit Windows

Version 2.1.4.16188

Improved scan of W2100 headstages
Bugfix: Minor fixes and improvements

Version 2.1.0.16124

Filter: Option to select trace visibility
Filter: Downsampling
New: Video synchronization with the W2100-System. Use the Multi Channel VideoControl tool to start synced video recording.

Version 2.0.0.0

New: SpikeDetecor with "Cutouts" Tab where spike overlays are displayed
New: Cross Channel Tool with "Pairwise Channel Operation" mode
W2100 stimulator: Events on stimulator single pulse or stimulation start
W2100 quality sideband data (check for packet losses over the air) is recorded automatically in the Recorder
New: Support for realtime feedback with MEA2100-Systems
New: Filter comes with predefined band pass settings
New: Sweep tool can display sweep count in the status bar
Bugfix: File name in the Recorder is saved in the Experiment Setup
Bugfix: MEA2100-6-well layout fixed

Version 1.6.3

Setting for DAC output voltage range for analog out in W2100-Systems
Setting in the Digital Event Detector whether the event LED is visible in the status bar
Bugfix for 60-6wellMEA layout in DAQ and Cross Channel instrument

Version 1.6.0

New: Sleep mode for W2100 headstage
New: Manual threshold in the Spike Detector
New: Channel selection in Filter tool
New: Status bar with event LEDs from the Digital Event Detector
Display pause button in Data Acquisition overview and Analog display

Version 1.5.1

New: Event pairs are stored in the "Event Based Export"

Version 1.5.0

New: Display of signal quality for every W2100 headstages.
Zoom display can be closed in the data acquisition display.

Version 1.4.1

New: Sweep Analyzer for analyzing sweep cutouts and export results to ASCII.
Saved experiment setups in subfolders are selectable.

Version 1.3.1

New: Audio out channel for W2100-Systems.
New: Cross Channel tool. Enables mathematical operations between data of different channels.
Fix for loading of experiment setups with MEA2100 stimulator.
Fix for loading experiment setups with ME64/128/256 data acquisition.
Several bugfixes for W2100-Systems.