Multiwell-Analyzer

Version 2.0.6.0

Version 2.0.2.0

Version 2.0.0.0

Version 1.8.7.0

• Bugfix: Ignore spike timestamps outside of the recording time range (produced by the Multiwell-Screen bug above)
• Bugfix: Fixed rare error due to numerical issue in Network Burst detector
• Bugfix: Fixed “Duration Lock” in “Edit Analysis Segments” dialog

Version 1.8.6.0

• Update: Support for new 96 well plate 96W700/100G-288
• Update: Neuro: Allow PSTH bin widths smaller than 10 ms
• Update: Neuro: Allow post-stimulus only triggered analysis
• Bugfix: Fixed Coefficient of Variation computation for Dose-Response Curves
• Bugfix: Neuro: Fixed spike threshold computation with multiple segments
• Bugfix: Cardio: Fixed heartbeat 2D latency analysis

Version 1.8.5.0

• Bugfix: Fixed error when loading specific cardio files

Version 1.8.4.0

• New Feature: Neuro: Triggered analysis on stimulation timestamps

• New Feature: Neuro: PSTH computation, display and export

• New Feature: Display of LED stimulation timestamps

• Update: Neuro: Channel Selection will select all channels in a well if "Min. Spikes per Minute" is 0 and "Min. Amplitude" deactivated

• Update: Tooltip for wells in Experiment View with phase durations/trigger counts

• Bugfix: Fixed time axis scaling in the raw data long term display for recordings with small sampling rates and short duration

• Bugfix: Neuro: Fixed spike count computation for network bursts

• Bugfix: Fixed crash when loading a file without wells

Version 1.7.1.0

• New Feature: Added button in Experiment View to display Multiwell-Screen settings during the recording and edit the Lab Book
• Update: Custom analysis time segments can be edited in the Time Segments dialog and copied to other wells
• Update: Custom analysis time segments may differ in duration in the "Define Analysis Segments" dialog of the Raw Data Explorer
• Update: Added export to Excel file format for analysis results
• Update: Support for new plate types
• Update: Support for new Cardio2D Layouts
• Bugfix: Lab Book is loaded properly and displayed in the import dialog for .mwa files
• Bugfix: Fixed possible error with "Only Active Wells" for Channel Selection
• Several minor bug fixes

Version 1.6.2.0

• New Feature: Cardio: Conduction Velocity (dose-response curves, pdf report and ASCII export)
• Bugfix: Cardio: Fixed Heartbeat 2D export to ASCII for non-cumulative dilution series
• Bugfix: Fixed segment analysis if one of the phases is shorter than the Control phase and the desired analysis duration
• Several UI and stability bug fixes

Version 1.6.1.0

• New Feature: Neuro: Network Burst Detection
• Update: Additional display options for long term display in Raw Data Explorer (stimuli, spikes/heartbeats, bursts, network bursts)
• Update: Improved UI for result export to CSV dialog
• Update: Neuro: New Network Burst Dose-Response Parameters in Dose-Response-Display
• Update: Neuro: New Network Burst options for results export to CSV
• Update: Neuro: Added Network Burst parameters to PDF report, reorganized well result tables
• Update: Cardio: Included new Cardio2D MEA layouts
• Bugfix: Fixed problems when Control phase was shorter than 1 second
• Bugfix: Fixed Common Segment (End) handling in Time Segment Configuration Dialog
• Bugfix: Fixed display of stimulation markers when switching between Channel and Dose view in Raw Data Explorer
• Bugfix: Cardio: Rerunning the Min-Max-Analysis should not delete manually defined T detections

Version 1.5.1.0

• Update: UI for merging freely labelled "dilution" series from multiple experiments
• Bugfix: Import Dialog: Fixed setting raw data and cutout folders for experiments within .mwa files
• Bugfix: Experiment Overview: Selected Channel highlight was not always updated properly

Version 1.4.5.0

• New feature: Cardio: Display for Min-Max Analysis
• New feature: Cardio: ASCII export of traces in Min-Max-Analysis
• Update: Redesign of the import dialog
• Update: Added support for new 96 well Mux plate
• Update: Highlight selected channels in the "Active Channels" overlay of the Experiment View
• Update: Highlight manually modified min/max detection points in the report and ASCII export
• Bugfix: "Active" state of channels was mistakenly set to false when a non-raw-data analysis was run:
• Bugfix: Revert mouse pointer to default after dragging of the spike threshold line is finished

Version 1.4.3.0

• Update: Support for new 96 well glass plate type

Version 1.4.2.0

• Update: Support for new 24 well glass plate
• Bugfix: Fixed display of highpass filters < 1 Hz in Filter Settings Dialog

Version 1.4.1.0

• New Feature: Cardio: Min-Max-Tool for analyzing peak-peak amplitudes in heartbeat-triggered averages
• Bugfix: Fixed legends in pdf report

Version 1.3.3.0

• New feature: Automatic check for updates
• Update: Support for 96 well plate with 1152 channels
• Lots of Bugfixes

Version 1.2.9.0

• Update: Support for new 24 well glass plate type
• Update: New "Analyze" button to start analysis
• Bugfix: Cardio: Fixed issues with import and export of Cardio2D files
• Bugfix: Fixed channel selection not running after raw data analysis
• Bugfix: Fixed crash when running analysis after changing the QT target

Version 1.2.3.0

• New feature: Import of Cardio2D Data (6-Well and 9-Well MEAs)
• Update: Cardio: Increased Average Duration Post and QT Search Stop Offset to 9.9 seconds
• Update: Cardio: ASCII Export of RR Interval CV

Version 1.1.6.0

• Update: Cardio: Added ASCII export of results to CiPA template
• Update: Improved identification of raw data and cutout files during import
• Bugfix: Cardio: Removed manually deactivated T detections from export
• Bugfix: Fixed crash when importing cutout file with invalid filter settings
• Bugfix: Fixed crash when importing file with deactivated channels

Version 1.1.4.0

• New feature: Display of analysis progress in Windows task bar
• Update: Neuro: Export spike amplitudes to ASCII
• Bugfix: Fixed error after analyzing merged experiments
• Bugfix: Fixed rarely occuring "endless" analysis
• Bugfix: Fixed display of help files if browser does not open .htm files by default
• Bugfix: Cardio: Allow simultaneous modification of QT search stop offset and Averager post interval.

Version 1.1.2.0

• New feature: Active Channels and wells: visualization and dose-response parameter
• New feature: Automatic channel selection instrument
• New feature: Neuro: Multiple selected channels per well
• New feature: Open .mwa and .mwr files directly per double click
• Update: Multiple predefined parameter sets for T detection
• Update: Show Y axis limits in long term display of raw data explorer
• Update: Synchronized layout of tab pages in raw data explorer
• Bugfix: Font scaling > 100 % prevented the software from starting
• Bugfix: Fixed possible freeze when switching between wells during analysis
• Bugfix: Fixed transfer of time segment settings between wells
• Bugfix: Fixed crash when importing files with manually deactivated first well

Version 1.0.1.0

• Bugfix: Cardio: Fixed reading of Noise Suppression parameter
• Bugfix: Cardio: Read/write of manually deselected T detections
• Bugfix: Neuro: Fixed burst detection for some special cases
• Bugfix: Fixed a rare crash after "Clear"

Version 1.0.0.0

• Analysis of neuronal data
• Software filter instrument
• Time segment instrument

Version 0.3.5

• Compatibility update with Multiwell-Screen 1.3.4
• Updated channel map for the 72 well plates

Version 0.3.4

• Initial release with support for cardio data